5-Hydroxy polymethoxyflavones inhibit glycosaminoglycan biosynthesis in lung and colon cancer cells

5-Hydroxy polymethoxyflavones inhibit glycosaminoglycan biosynthesis in lung and colon cancer cells

5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone (5HHMF) and 5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone (5HPMF) are the predominant polymethoxyflavones in orange peel. Here, we showed how 5HHMF or 5HPMF modulated the amount of pre-existing and newly synthesized glycosaminoglycans (GAG) in lung and colon ca...

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Bibliographic Details
Main Authors: Peiju Qiu, Yidi Cui, Hang Xiao, Zhangrun Han, He Ma, Yang Tang, Huixin Xu, Lijuan Zhang
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Functional Foods
Subjects:
5HHMF
5HPMF
LC/MS
PMP
Heparan sulfate
Condroitin sulfate
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617300087

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http://www.sciencedirect.com/science/article/pii/S1756464617300087

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