Identification and Total Synthesis of Two Previously Unreported Odd-Chain Bis-Methylene-Interrupted Fatty Acids with a Terminal Olefin that Activate Protein Phosphatase, Mg<sup>2+</sup>/Mn<sup>2+</sup>-Dependent 1A (PPM1A) in Ovaries of the Limpet <i>Cellana toreuma</i>

Identification and Total Synthesis of Two Previously Unreported Odd-Chain Bis-Methylene-Interrupted Fatty Acids with a Terminal Olefin that Activate Protein Phosphatase, Mg<sup>2+</sup>/Mn<sup>2+</sup>-Dependent 1A (PPM1A) in Ovaries of the Limpet <i>Cellana toreuma</i>

Diverse non-methylene-interrupted (NMI) fatty acids (FAs) with odd-chain lengths have been recognized in triacylglycerols and polar lipids from the ovaries of the limpet <i>Cellana toreuma</i>, however their biological properties remain unclear. In this study, two previously unreported o...

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Bibliographic Details
Main Authors: Hideki Kawashima, Naoki Toyooka, Takuya Okada, Huy Du Nguyen, Yuya Nishikawa, Yuka Miura, Nana Inoue, Ken-ichi Kimura
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Marine Drugs
Subjects:
non-methylene-interrupted fatty acids
bis-methylene-interrupted dienoic acids
limpet
<i>Cellana toreuma</i>
cytotoxicity
(12<i>Z</i>)-12,16-heptadecadienoic acid
(14<i>Z</i>)-14,18-nonadecadienoic acid
equivalent chain length
protein phosphatase, Mg<sup>2+</sup>/Mn<sup>2+</sup>-dependent 1A (PPM1A)
Online Access:https://www.mdpi.com/1660-3397/17/7/410

Internet

https://www.mdpi.com/1660-3397/17/7/410

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