Deficit in motor training-induced clustering, but not stabilization, of new dendritic spines in FMR1 knock-out mice.

Fragile X Syndrome is the most common inherited intellectual disability, and Fragile X Syndrome patients often exhibit motor and learning deficits. It was previously shown that the fmr1 knock-out mice, a common mouse model of Fragile X Syndrome, recapitulates this motor learning deficit and that the...

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Bibliographic Details
Main Authors: Benjamin C Reiner, Anna Dunaevsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4423947?pdf=render