Enhanced SPARCL1 expression in cancer stem cells improves preclinical modeling of glioblastoma by promoting both tumor infiltration and angiogenesis

Enhanced SPARCL1 expression in cancer stem cells improves preclinical modeling of glioblastoma by promoting both tumor infiltration and angiogenesis

Glioblastoma (GBM) is the most malignant brain tumor of adults and is characterized by extensive cell dissemination within the brain parenchyma and enhanced angiogenesis. Effective preclinical modeling of these key features suffers from several shortcomings. Aim of this study was to determine whethe...

Full description

Bibliographic Details
Main Authors: Filippo Gagliardi, Ashwin Narayanan, Alberto Luigi Gallotti, Valentina Pieri, Stefania Mazzoleni, Manuela Cominelli, Sara Rezzola, Michela Corsini, Gianluca Brugnara, Luisa Altabella, Letterio Salvatore Politi, Marco Bacigaluppi, Andrea Falini, Antonella Castellano, Roberto Ronca, Pietro Luigi Poliani, Pietro Mortini, Rossella Galli
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303808

Internet

http://www.sciencedirect.com/science/article/pii/S0969996119303808

Similar Items