The H3.3K27M oncohistone antagonizes reprogramming in Drosophila.

Development proceeds by the activation of genes by transcription factors and the inactivation of others by chromatin-mediated gene silencing. In certain cases development can be reversed or redirected by mis-expression of master regulator transcription factors. This must involve the activation of pr...

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Bibliographic Details
Main Authors: Kami Ahmad, Steven Henikoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009225