The H3.3K27M oncohistone antagonizes reprogramming in Drosophila.
Development proceeds by the activation of genes by transcription factors and the inactivation of others by chromatin-mediated gene silencing. In certain cases development can be reversed or redirected by mis-expression of master regulator transcription factors. This must involve the activation of pr...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-07-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009225 |