In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

Computational chemistry has now been widely accepted as a useful tool for shortening lead times in early drug discovery. When selecting new potential drug targets, it is important to assess the likelihood of finding suitable starting points for lead generation before pursuing costly high-throughput...

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Bibliographic Details
Main Authors: Maurice Michel, Evert J. Homan, Elisée Wiita, Kia Pedersen, Ingrid Almlöf, Anna-Lena Gustavsson, Thomas Lundbäck, Thomas Helleday, Ulrika Warpman Berglund
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Chemistry
Subjects:
druggability
nudix
drug discovery
workflow
malachite green
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00443/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00443/full

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