The implications of outcome truncation in reproductive medicine RCTs: a simulation platform for trialists and simulation study

Abstract Background Randomised controlled trials in reproductive medicine are often subject to outcome truncation, where the study outcomes are only defined in a subset of the randomised cohort. Examples include birthweight (measurable only in the subgroup of participants who give birth) and miscarr...

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Bibliographic Details
Main Authors: Jack Wilkinson, Jonathan Y. Huang, Antonia Marsden, Michael O. Harhay, Andy Vail, Stephen A. Roberts
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-021-05482-4