Crystal structures of two chiral piperidine derivatives: 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one and 8-[(1S)-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione

Crystal structures of two chiral piperidine derivatives: 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one and 8-[(1S)-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione

The crystal structures of the two title piperidine derivatives show different conformations for the six-membered heterocycle. The N-substituted 4-piperidinone 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one, C13H17NO2, (I), has a chair conformation, while the piperidine substituted in position 2 wit...

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Bibliographic Details
Main Authors: Nancy Romero, Sylvain Bernès, Luis F. Roa, Joel L. Terán, Dino Gnecco
Format: Article
Language:English
Published: International Union of Crystallography 2015-10-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
piperidine
piperidone
thione
ring conformation
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989015017119

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http://scripts.iucr.org/cgi-bin/paper?S2056989015017119

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