The relationship between expression of PD-L1 and HIF-1α in glioma cells under hypoxia

The relationship between expression of PD-L1 and HIF-1α in glioma cells under hypoxia

Abstract Hypoxia inducible factor-1α (HIF-1α) up-regulates the expression of programmed death ligand-1 (PD-L1) in some extracranial malignancies. However, whether it could increase PD-L1 expression in intracranial tumor is still unknown. Here, we explored the relationship between HIF-1α and PD-L1 ex...

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Bibliographic Details
Main Authors: Xing-chen Ding, Liang-liang Wang, Xue-dong Zhang, Jun-long Xu, Pei-feng Li, Hua Liang, Xian-bin Zhang, Li Xie, Zi-han Zhou, Jia Yang, Ralph R. Weichselbaum, Jin-ming Yu, Man Hu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Hematology & Oncology
Subjects:
PD-L1
HIF-1 α
Glioma
Hypoxia
Immunotherapy
Online Access:https://doi.org/10.1186/s13045-021-01102-5

Internet

https://doi.org/10.1186/s13045-021-01102-5

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