Panax notoginseng saponins promotes cerebral recovery from ischemic injury by downregulating LINGO-1 and activating the EGFR/PI3K/AKT signaling pathways in vivo

Panax notoginseng saponins promotes cerebral recovery from ischemic injury by downregulating LINGO-1 and activating the EGFR/PI3K/AKT signaling pathways in vivo

Objective: Panax notoginseng saponins (PNS), extracted from rhizome of the herb Radix et Rhizoma Notoginseng (Panax notoginseng (Burk.) F.H. Chen), was recently discovered to have beneficial effects against neurological damage. This study investigated the effects of PNS on cerebral ischemia and eluc...

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Bibliographic Details
Main Authors: Tiantian Yang, Qi Guo, Xiaowei Shi, Shuang Wu, Ya Li, Yikun Sun, Yizhou Zhao, Limin Chai, Yonghong Gao, Lixia Lou, Bin Dong, Lingqun Zhu
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Journal of Traditional Chinese Medical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S209575481730193X

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http://www.sciencedirect.com/science/article/pii/S209575481730193X

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