High Throughput miRNA Screening Identifies miR-574-3p Hyperproductive Effect in CHO Cells

High Throughput miRNA Screening Identifies miR-574-3p Hyperproductive Effect in CHO Cells

CHO is the cell line of choice for the manufacturing of many complex biotherapeutics. The constant upgrading of cell productivity is needed to meet the growing demand for these life-saving drugs. Manipulation of small non-coding RNAs—miRNAs—is a good alternative to a single gene knockdown approach d...

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Bibliographic Details
Main Authors: Živa Švab, Luca Braga, Corrado Guarnaccia, Ivan Labik, Jeremias Herzog, Marco Baralle, Mauro Giacca, Nataša Skoko
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
miRNA screening
miR-574-3p
hyperproductivity
CHO
pri-miRNA processing
p300
Online Access:https://www.mdpi.com/2218-273X/11/8/1125

Internet

https://www.mdpi.com/2218-273X/11/8/1125

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