Impact of Key Nicotinic AChR Subunits on Post-Stroke Pneumococcal Pneumonia

Pneumonia is the most frequent severe medical complication after stroke. An overactivation of the cholinergic signaling after stroke contributes to immunosuppression and the development of spontaneous pneumonia caused by Gram-negative pathogens. The α7 nicotinic acetylcholine receptor (α7nAChR) has...

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Bibliographic Details
Main Authors: Sandra Jagdmann, Claudia Dames, Daniel Berchtold, Katarzyna Winek, Luis Weitbrecht, Andreas Meisel, Christian Meisel
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/2/253