C-di-GMP Regulates Motile to Sessile Transition by Modulating MshA Pili Biogenesis and Near-Surface Motility Behavior in Vibrio cholerae.

In many bacteria, including Vibrio cholerae, cyclic dimeric guanosine monophosphate (c-di-GMP) controls the motile to biofilm life style switch. Yet, little is known about how this occurs. In this study, we report that changes in c-di-GMP concentration impact the biosynthesis of the MshA pili, resul...

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Bibliographic Details
Main Authors: Christopher J Jones, Andrew Utada, Kimberly R Davis, Wiriya Thongsomboon, David Zamorano Sanchez, Vinita Banakar, Lynette Cegelski, Gerard C L Wong, Fitnat H Yildiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4624765?pdf=render