Leptin gene variants and colorectal cancer risk: Sex-specific associations.

BACKGROUND:High levels of serum leptin and low levels of serum adiponectin are strongly correlated with obesity, a well-established risk factor for colorectal cancer (CRC). Growing evidence suggests that dysregulation of leptin and adiponectin levels may play an etiological role in colorectal carcin...

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Bibliographic Details
Main Authors: Kelsey A Chun, Jonathan M Kocarnik, Sheetal S Hardikar, Jamaica R Robinson, Sonja I Berndt, Andrew T Chan, Jane C Figueiredo, Noralane M Lindor, Mingyang Song, Robert E Schoen, Richard B Hayes, John D Potter, Rami Nassir, Stéphane Bézieau, Loic Le Marchand, Martha L Slattery, Emily White, Ulrike Peters, Polly A Newcomb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6209341?pdf=render