Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area

Cocaine is a highly addictive drug that acts upon the brain’s reward circuitry via the inhibition of monoamine uptake. Endogenous cannabinoids (eCB) are lipid molecules released from midbrain dopamine (DA) neurons that modulate cocaine’s effects through poorly understood mechanisms. We find that coc...

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Bibliographic Details
Main Authors: Huikun Wang, Tyler Treadway, Daniel P. Covey, Joseph F. Cheer, Carl R. Lupica
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009262