A novel DC therapy with manipulation of MKK6 gene on nickel allergy in mice.

A novel DC therapy with manipulation of MKK6 gene on nickel allergy in mice.

Although the activation of dermal dendritic cells (DCs) or Langerhans cells (LCs) via p38 mitogen-activated protein kinase (MAPK) plays a crucial role in the pathogenesis of metal allergy, the in vivo molecular mechanisms have not been identified and a possible therapeutic strategy using the control...

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Bibliographic Details
Main Authors: Megumi Watanabe, Naozumi Ishimaru, Meinar Nur Ashrin, Rieko Arakaki, Akiko Yamada, Tetsuo Ichikawa, Yoshio Hayashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3081319?pdf=render

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http://europepmc.org/articles/PMC3081319?pdf=render

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