Validation of diffusion tensor imaging measures of nigrostriatal neurons in macaques.

OBJECTIVE:Interpretation of diffusion MRI in the living brain requires validation against gold standard histological measures. We compared diffusion values of the nigrostriatal tract to PET and histological results in non-human primates (NHPs) with varying degrees of unilateral nigrostriatal injury...

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Bibliographic Details
Main Authors: Joshua S Shimony, Jerrel Rutlin, Morvarid Karimi, Linlin Tian, Abraham Z Snyder, Susan K Loftin, Scott A Norris, Joel S Perlmutter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6124722?pdf=render