Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling

Aberrant DNA methylation patterns in malignant cells allow insight into tumor evolution and development and can be used for disease classification. Here, we describe the genome-wide DNA methylation signatures of NPM-ALK-positive (ALK+) and NPM-ALK-negative (ALK−) anaplastic large-cell lymphoma (ALCL...

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Bibliographic Details
Main Authors: Melanie R. Hassler, Walter Pulverer, Ranjani Lakshminarasimhan, Elisa Redl, Julia Hacker, Gavin D. Garland, Olaf Merkel, Ana-Iris Schiefer, Ingrid Simonitsch-Klupp, Lukas Kenner, Daniel J. Weisenberger, Andreas Weinhaeusel, Suzanne D. Turner, Gerda Egger
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Subjects:
DNA methylation
NPM-ALK
anaplastic large-cell lymphoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312402

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http://www.sciencedirect.com/science/article/pii/S2211124716312402

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