Statistical method on nonrandom clustering with application to somatic mutations in cancer

<p>Abstract</p> <p>Background</p> <p>Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a consequence of genomic instability and high levels of proliferation, ma...

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Bibliographic Details
Main Authors: Rejto Paul A, Lunney Elizabeth A, Pavlicek Adam, Ye Jingjing, Teng Chi-Hse
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/11