Dissecting the binding mechanisms of transcription factors to DNA using a statistical thermodynamics framework

Transcription Factors (TFs) bind to DNA and control activity of target genes. Here, we present ChIPanalyser, a user-friendly, versatile and powerful R/Bioconductor package predicting and modelling the binding of TFs to DNA. ChIPanalyser performs similarly to state-of-the-art tools, but is an explain...

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Bibliographic Details
Main Authors: Patrick C.N. Martin, Nicolae Radu Zabet
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020304736