Intravital Metabolic Autofluorescence Imaging Captures Macrophage Heterogeneity Across Normal and Cancerous Tissue

Macrophages are dynamic immune cells that govern both normal tissue function and disease progression. However, standard methods to measure heterogeneity in macrophage function within tissues require tissue excision and fixation, which limits our understanding of diverse macrophage function in vivo....

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Bibliographic Details
Main Authors: Tiffany M. Heaster, Alexa R. Heaton, Paul M. Sondel, Melissa C. Skala
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.644648/full