CG7379 and ING1 suppress cancer cell invasion by maintaining cell–cell junction integrity
Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a potent invasion suppressor. ING1 is a type II tumour suppressor with well-established roles in the transcriptional regulation of genes...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2021-09-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.210077 |