A Logic Model of Neuronal-Glial Interaction Suggests Altered Homeostatic Regulation in the Perpetuation of Neuroinflammation

A Logic Model of Neuronal-Glial Interaction Suggests Altered Homeostatic Regulation in the Perpetuation of Neuroinflammation

Aberrant inflammatory signaling between neuronal and glial cells can develop into a persistent sickness behavior-related disorders, negatively impacting learning, memory, and neurogenesis. While there is an abundance of literature describing these interactions, there still lacks a comprehensive math...

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Bibliographic Details
Main Authors: Travis J. A. Craddock, Lindsay T. Michalovicz, Kimberly A. Kelly, Mark A. Rice, Diane B. Miller, Nancy G. Klimas, Mariana Morris, James P. O'Callaghan, Gordon Broderick
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuroinflammation
logical modeling
systems neuroscience
regulatory biology
homeostatic regulation
treatment course prediction
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00336/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00336/full

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