The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration.

The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration.

Transition metals are necessary for all forms of life including microorganisms, evidenced by the fact that 30% of all proteins are predicted to interact with a metal cofactor. Through a process termed nutritional immunity, the host actively sequesters essential nutrient metals away from invading pat...

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Bibliographic Details
Main Authors: Jennifer A Gaddy, Jana N Radin, John T Loh, M Blanca Piazuelo, Thomas E Kehl-Fie, Alberto G Delgado, Florin T Ilca, Richard M Peek, Timothy L Cover, Walter J Chazin, Eric P Skaar, Holly M Scott Algood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4199781?pdf=render

Internet

http://europepmc.org/articles/PMC4199781?pdf=render

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