Outcome pre-specification requires sufficient detail to guard against outcome switching in clinical trials: a case study
Abstract Background Pre-specification of outcomes is an important tool to guard against outcome switching in clinical trials. However, if the outcome is not sufficiently clearly defined, then different definitions could be applied and analysed, with only the most favourable result reported. Methods...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-05-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-018-2654-z |