Caprine MAVS Is a RIG-I Interacting Type I Interferon Inducer Downregulated by Peste des Petits Ruminants Virus Infection

Caprine MAVS Is a RIG-I Interacting Type I Interferon Inducer Downregulated by Peste des Petits Ruminants Virus Infection

The mitochondrial antiviral-signaling protein (MAVS, also known as VISA, IPS-1, or CARDIF) plays an essential role in the type I interferon (IFN) response and in retinoic acid-inducible gene I (RIG-I) mediated antiviral innate immunity in mammals. In this study, the caprine MAVS gene (caMAVS, 1566 b...

Full description

Bibliographic Details
Main Authors: Qiuhong Miao, Ruibing Qi, Chunchun Meng, Jie Zhu, Aoxing Tang, Dandan Dong, Hongyuan Guo, Monique M. van Oers, Gorben P. Pijlman, Guangqing Liu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
caprine
mitochondrial antiviral signaling protein (MAVS)
Peste des Petits Ruminants Virus (PPRV)
innate immunity
Online Access:https://www.mdpi.com/1999-4915/13/3/409

Internet

https://www.mdpi.com/1999-4915/13/3/409

Similar Items