Increased sphingosine-1-phosphate production in response to osteocyte mechanotransduction

Over the past few years interest has greatly increased in how the lipid mediator sphingosine-1-phosphate (S1P) influences bone homeostasis. Recent work has postulated multiple effects of S1P on osteoblasts and osteoclasts. Based on these findings, S1P has been proposed as a potential osteoporosis tr...

Full description

Bibliographic Details
Main Authors: Cale Dobrosak, Jonathan H. Gooi
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Bone Reports
Subjects:
S1P
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187217300311