The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes.

The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes.

Epidermolysis bullosa simplex (EBS) is an inherited skin-blistering disease that is caused by dominant mutations in the genes for keratin K5 or K14 proteins. While the link between keratin mutations and keratinocyte fragility in EBS patients is clear, the exact biophysical mechanisms underlying cell...

Full description

Bibliographic Details
Main Authors: Daniel R Beriault, Oualid Haddad, John V McCuaig, Zachary J Robinson, David Russell, E Birgitte Lane, Douglas S Fudge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283645?pdf=render

Internet

http://europepmc.org/articles/PMC3283645?pdf=render

Similar Items