Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix

Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix

The metaplastic epithelium of the transformation zone (TZ) including the squamocolumnar junction (SCJ) of the uterine cervix is a prime target of human papilloma virus (HPV) infection and subsequent cancer development. Due to the lack of adequate in vitro models for SCJ, however, investigations into...

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Bibliographic Details
Main Authors: Yoshiaki Maru, Akira Kawata, Ayumi Taguchi, Yoshiyuki Ishii, Satoshi Baba, Mayuyo Mori, Takeshi Nagamatsu, Katsutoshi Oda, Iwao Kukimoto, Yutaka Osuga, Tomoyuki Fujii, Yoshitaka Hippo
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
organoid
uterine cervix
squamocolumnar junction
human papillomavirus
matrigel
Online Access:https://www.mdpi.com/2072-6694/12/3/694

Internet

https://www.mdpi.com/2072-6694/12/3/694

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