A nucleosome-guided map of transcription factor binding sites in yeast.

Finding functional DNA binding sites of transcription factors (TFs) throughout the genome is a crucial step in understanding transcriptional regulation. Unfortunately, these binding sites are typically short and degenerate, posing a significant statistical challenge: many more matches to known TF mo...

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Bibliographic Details
Main Authors: Leelavati Narlikar, Raluca Gordân, Alexander J Hartemink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2065891?pdf=render