Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis.

Plasma concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, are raised in patients with chronic vascular disease, causing increased cardiovascular risk and endothelial dysfunction, but the role of ADMA in acute inflammatory states is less well defin...

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Bibliographic Details
Main Authors: Joshua S Davis, Christabelle J Darcy, Tsin W Yeo, Catherine Jones, Yvette R McNeil, Dianne P Stephens, David S Celermajer, Nicholas M Anstey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3041798?pdf=render