Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function.

To compare drug efflux function of ABCB1 and ABCG2 transporters in rheumatoid arthritis (RA) patients with active disease and in remission.Twenty two active RA patients (DAS28 ≥3.2) and 22 patients in remission (DAS28<2.6) were selected from an early RA clinic. All patients were evaluated at stud...

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Main Authors: Yemil Atisha-Fregoso, Guadalupe Lima, Virginia Pascual-Ramos, Miguel Baños-Peláez, Hilda Fragoso-Loyo, Juan Jakez-Ocampo, Irazú Contreras-Yáñez, Luis Llorente
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4956301?pdf=render