Aging Reduces the Neuroprotective Capacity, VEGF Secretion, and Metabolic Activity of Rat Choroid Plexus Epithelial Cells

Delivery of neurotrophic molecules to the brain has potential for preventing neuronal loss in neurodegenerative disorders. Choroid plexus (CP) epithelial cells secrete numerous neurotrophic factors, and encapsulated CP transplants are neuroprotective in models of stroke and Huntington's disease...

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Bibliographic Details
Main Authors: Dwaine F. Emerich, Patricia Schneider, Briannan Bintz, Jebecka Hudak, Christopher G. Thanos
Format: Article
Language:English
Published: SAGE Publishing 2007-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000007783465145