Galactosylceramide affects tumorigenic and metastatic properties of breast cancer cells as an anti-apoptotic molecule.

Galactosylceramide affects tumorigenic and metastatic properties of breast cancer cells as an anti-apoptotic molecule.

It was recently proposed that UDP-galactose:ceramide galactosyltransferase (UGT8), enzyme responsible for synthesis of galactosylceramide (GalCer), is a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. To further reve...

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Bibliographic Details
Main Authors: Tomasz B Owczarek, Jarosław Suchanski, Bartosz Pula, Alicja M Kmiecik, Marek Chadalski, Aleksandra Jethon, Piotr Dziegiel, Maciej Ugorski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877204?pdf=render

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http://europepmc.org/articles/PMC3877204?pdf=render

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