Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies

Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies

Established bacterial glycoengineering platforms limit access to protein and glycan substrates. Here the authors design a cytoplasmic protein glycosylation system, Glycoli, to generate a variety of multivalent glycostructures.

Bibliographic Details
Main Authors: Hanne L. P. Tytgat, Chia-wei Lin, Mikail D. Levasseur, Markus B. Tomek, Christoph Rutschmann, Jacqueline Mock, Nora Liebscher, Naohiro Terasaka, Yusuke Azuma, Michael Wetter, Martin F. Bachmann, Donald Hilvert, Markus Aebi, Timothy G. Keys
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13283-2

Internet

https://doi.org/10.1038/s41467-019-13283-2

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