Chemotherapy effectiveness in trial-underrepresented groups with early breast cancer: A retrospective cohort study.

BACKGROUND:Adjuvant chemotherapy in early stage breast cancer has been shown to reduce mortality in a large meta-analysis of over 100 randomised trials. However, these trials largely excluded patients aged 70 years and over or with higher levels of comorbidity. There is therefore uncertainty about w...

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Bibliographic Details
Main Authors: Ewan Gray, Joachim Marti, Jeremy C Wyatt, David H Brewster, Peter S Hall, SATURNE advisory group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003006