Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance

Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance

Cells undergoing xenobiotic or oxidative stress activate the transcription factor nuclear factor erythroid-derived 2-like 2 (Nrf2), which initiates an intrinsic “stress surveillance” pathway. We recently found that the cytokine IL-17D effects a form of extrinsic stress surveillance by inducing antit...

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Bibliographic Details
Main Authors: Robert Saddawi-Konefka, Ruth Seelige, Emilie T.E. Gross, Eric Levy, Stephen C. Searles, Allen Washington Jr., Endi K. Santosa, Beichen Liu, Timothy E. O’Sullivan, Olivier Harismendy, Jack D. Bui
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Subjects:
immunosurveillance
innate immunity
interleukin-17D
NK cells
Nrf2
tumor rejection
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471631021X

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http://www.sciencedirect.com/science/article/pii/S221112471631021X

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