Aberrantly Methylated MGMT, hMLH1 and hMSH2 in Tumor and Serum DNA of Gliomas Patients
OBJECTIVE This study is to investigate the prevalence of promoter CpG island methylation of O6-methylguananine-DNA methyltransferase (MGMT), mismatch repair genes ( hMLH1 and hMSH2) in both tumor and serum samples of gliomas.METHODS Methylation-specific PCR (MSP) was employed to detect promot...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2009-02-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/172 |