Smurf1 Silencing Using a LNA‐ASOs/Lipid Nanoparticle System to Promote Bone Regeneration

Smurf1 Silencing Using a LNA‐ASOs/Lipid Nanoparticle System to Promote Bone Regeneration

Abstract Despite the great advance of bone tissue engineering in the last few years, repair of bone defects remains a major problem. Low cell engraftment and dose‐dependent side effects linked to the concomitant administration of bone morphogenetic proteins (BMPs) are the main problems currently hin...

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Bibliographic Details
Main Authors: Patricia García‐García, Mario Ruiz, Ricardo Reyes, Araceli Delgado, Carmen Évora, José Antonio Riancho, José Carlos Rodríguez‐Rey, Flor María Pérez‐Campo
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Stem Cells Translational Medicine
Subjects:
Mesenchymal stem cells
Bone regeneration
LNA‐ASO
GapmeR
Smurf1
Osteogenesis
Online Access:https://doi.org/10.1002/sctm.19-0145

Internet

https://doi.org/10.1002/sctm.19-0145

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