Comprehending Meningioma Signaling Cascades Using Multipronged Proteomics Approaches & Targeted Validation of Potential Markers

Comprehending Meningioma Signaling Cascades Using Multipronged Proteomics Approaches & Targeted Validation of Potential Markers

Meningiomas are one of the most prevalent primary brain tumors. Our study aims to obtain mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free quantitative proteome analysis to identifying druggable targets and perturbed pathways for therapeutic intervention. Label...

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Bibliographic Details
Main Authors: Shuvolina Mukherjee, Deeptarup Biswas, Rucha Gadre, Pooja Jain, Nelofer Syed, Julianna Stylianou, Qingyu Zeng, Anita Mahadevan, Sridhar Epari, Prakash Shetty, Aliasgar Moiyadi, Graham Roy Ball, Sanjeeva Srivastava
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
label-free proteomics
meningioma tissue
patient-derived primary cell line
RT2 PCR arrays
Integrin Linked Kinase inhibition
Integrin pathway
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01600/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01600/full

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