Progeria: A rare genetic premature ageing disorder

Progeria: A rare genetic premature ageing disorder

Progeria is characterized by clinical features that mimic premature ageing. Although the mutation responsible for this syndrome has been deciphered, the mechanism of its action remains elusive. Progeria research has gained momentum particularly in the last two decades because of the possibility of r...

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Bibliographic Details
Main Authors: Jitendra Kumar Sinha, Shampa Ghosh, Manchala Raghunath
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Journal of Medical Research
Subjects:
Accelerated ageing - clinical trial - experimental models - farnesylation - Hutchinson-Gilford progeria syndrome - lamin A - LMNA gene - lonafarnib - longevity
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=5;spage=667;epage=674;aulast=Sinha

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=5;spage=667;epage=674;aulast=Sinha

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