An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment

An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment

Regulatory T cells (Tregs) play a pivotal role in maintaining immunological tolerance, but they can also play a detrimental role by preventing antitumor responses. Here, we characterized T helper (Th)-like Treg subsets to further delineate their biological function and tissue distribution, focusing...

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Bibliographic Details
Main Authors: Leena Halim, Marco Romano, Reuben McGregor, Isabel Correa, Polychronis Pavlidis, Nathali Grageda, Sec-Julie Hoong, Muhammed Yuksel, Wayel Jassem, Rosalind F. Hannen, Mark Ong, Olivia Mckinney, Bu’Hussain Hayee, Sophia N. Karagiannis, Nicholas Powell, Robert I. Lechler, Estefania Nova-Lamperti, Giovanna Lombardi
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Cell Reports
Subjects:
T helper-like regulatory cells
chemokine receptor
tumor immunity
immunoregulation
tumor immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717309270

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http://www.sciencedirect.com/science/article/pii/S2211124717309270

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