Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice.

Toll-like receptors (TLRs) play an important role in the induction of innate and adaptive immune response against influenza A virus (IAV) infection; however, the role of Toll-like receptor 7 (TLR7) during the innate immune response to IAV infection and the cell types affected by the absence of TLR7...

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Bibliographic Details
Main Authors: Victoria Jeisy-Scott, William G Davis, Jenish R Patel, John Bradford Bowzard, Wun-Ju Shieh, Sherif R Zaki, Jacqueline M Katz, Suryaprakash Sambhara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3179470?pdf=render