Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections. Nuclear factor-κB is a key component of the TLR-pathway, controlled by inhibitors, encoded by the genes NF...

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Bibliographic Details
Main Authors: Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:EBioMedicine
Subjects:
Invasive Pneumococcal Disease
Invasive Meningococcal Disease
Nuclear Factor-κB
Pneumoccoccal Serotypes
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415302310

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http://www.sciencedirect.com/science/article/pii/S2352396415302310

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