Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies.

Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott ArchitectTM SARS-CoV-2 IgG assay indicated that the assays had high concordance...

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Bibliographic Details
Main Authors: Ashutosh Wadhwa, Sherry Yin, Brandi Freeman, Rebecca B Hershow, Marie Killerby, Anna R Yousaf, Sandra Lester, Lisa Mills, Sean A Buono, Mary Pomeroy, Daniel Owusu, Victoria T Chu, Jacqueline E Tate, Sanjib Bhattacharyya, Patricia Hall, Natalie J Thornburg, Hannah L Kirking
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0255208