Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells

<p>Abstract</p> <p>Background</p> <p>Pulmonary arterial hypertension is a proliferative vascular disease, characterized by aberrant regulation of smooth muscle cell proliferation and apoptosis in distal pulmonary arteries. Prostacyclin (PGI<sub>2</sub>) anal...

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Bibliographic Details
Main Authors: Afzal Saliha, Ren Xiaohui, Spink Karen G, Growcott Ellena J, Banner Kathy H, Wharton John
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/9