Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster.
Deletions, commonly referred to as deficiencies by Drosophila geneticists, are valuable tools for mapping genes and for genetic pathway discovery via dose-dependent suppressor and enhancer screens. More recently, it has become clear that deviations from normal gene dosage are associated with multipl...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-09-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC5012587?pdf=render |