The Transcription Factor SUB1 Is a Master Regulator of the Macrophage TLR Response in Atherosclerosis

The Transcription Factor SUB1 Is a Master Regulator of the Macrophage TLR Response in Atherosclerosis

Abstract Toll‐like receptor 2 and 4 (TLR2, TLR4) signaling is implicated in atherosclerotic plaque formation. The two‐stage master regulator Virtual Inference of Protein‐activity by Enriched Regulon (VIPER) analysis of macrophage TLR2 and TLR4 signature genes integrated with coexpression network gen...

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Bibliographic Details
Main Authors: Rongzhong Huang, Zicheng Hu, Xiaorui Chen, Yu Cao, Hongrong Li, Hong Zhang, Yongyong Li, Liwen Liang, Yuxing Feng, Ying Wang, Wenhua Su, Zerui Kong, ND Melgiri, Lihong Jiang, Xingsheng Li, Jianlin Du, Yunqing Chen
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Advanced Science
Subjects:
atherosclerosis
PC4
SUB1
TLR2
TLR4, Toll‐like receptor
Online Access:https://doi.org/10.1002/advs.202004162

Internet

https://doi.org/10.1002/advs.202004162

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