Interactions of MCP1 with Components of the Replication Machinery in Mammalian Cells

<p>Eukaryotic DNA replication starts with the assembly of a pre-replication complex (pre-RC) at replication origins. We have previously demonstrated that Metaphase Chromosome Protein 1 (MCP1) is involved in the early events of DNA replication. Here we show that MCP1 associates with proteins th...

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Bibliographic Details
Main Author: Elsa Bronze-da-Rocha, Chii-Mei Lin, Tsutomu Shimura, Mirit I. Aladjem
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v07p0193.htm