Participation of Gαi-Adenylate Cyclase and ERK1/2 in Mas Receptor Signaling Pathways

Participation of Gαi-Adenylate Cyclase and ERK1/2 in Mas Receptor Signaling Pathways

The MasR receptor (MasR) is an orphan G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang-(1–7) protective axis of renin-angiotensin system. This receptor has been suggested to participate in several physiological processes including cardio-...

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Bibliographic Details
Main Authors: Valeria Burghi, Emiliana B. Echeverría, Máximo H. Sosa, Diego T. Quiroga, Marina C. Muñoz, Carlos Davio, Federico Monczor, Natalia C. Fernández, Fernando P. Dominici
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Pharmacology
Subjects:
angiotensin-(1-7)
cAMP
ERK
G protein-coupled receptor
Mas receptor
signaling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00146/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00146/full

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